What famous highway runs through Nebraska?

Interstate 80 is the highway that runs through Nebraska and serves as a major east-west route across the state. This interstate connects various significant cities and resources, facilitating travel and commerce. It provides an essential link for transportation and is one of the few transcontinental highways in the United States.

U.S. Route 66, though historically famous for its cultural significance, does not run through Nebraska, as it primarily traverses the southern United States. Likewise, U.S. Route 80 and U.S. Route 10 do not pass through Nebraska, with Route 80 mainly extending across southern states and Route 10 primarily running in the west. Therefore, Interstate 80 stands as the notable highway that runs through Nebraska, playing a crucial role in the state's infrastructure and connectivity.